Search on: WATERHOUSE-FRIDERICHSEN SYNDROME 
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Descriptor English:   Waterhouse-Friderichsen Syndrome 
Descriptor Spanish:   Síndrome de Waterhouse-Friderichsen 
Descriptor Portuguese:   Síndrome de Waterhouse-Friderichsen 
Synonyms English:   Fulminant Meningococcal Sepsis with Adrenal Apoplexy
Meningococcal Hemorrhagic Adrenalitis
Purpura Fulminans (Waterhouse-Friderichsen Syndrome)  
Tree Number:   C01.252.200.500.550.800
C01.252.400.625.549.449.800
C10.228.228.180.500.750.500
C10.228.228.507.280.505.904
C15.378.463.950
C19.053.500.740
Definition English:   A condition caused by overwhelming BACTERIAL INFECTIONS or SEPTICEMIA, leading to HEMORRHAGE and NECROSIS of the ADRENAL GLAND. It is characterized by rapidly developing ADRENAL INSUFFICIENCY; HYPOTENSION; and widespread cutaneous PURPURA. This syndrome may occur at any age but is more common in children. 
Indexing Annotation English:   do not coord with NEISSERIA MENINGITIDIS unless particularly discussed; if caused by other organism, coord IM with precoord organism/infection term
History Note English:   1991, 1963-1983; use MENINGOCOCCAL INFECTIONS 1984-1990 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy TM transmission
US ultrasonography UR urine
VE veterinary VI virology
Record Number:   15286 
Unique Identifier:   D014884 

Occurrence in VHL: 		 

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